DRUCKER LABS IntraMAX – Organic, Liquid, Trace Minerals, Multivitamin and Multi-Nutritional Dietary Supplement (32 Ounce / 946 Milliliter, Peach Mango Flavor)

★★★★★ Totally worth it for me to take based on the below:The science behind Niagen (nicotinamide riboside, NR) becoming a large product category.:1) Nicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells. There are hundreds of cellular processes that rely on NAD+ from mitochondrial function turning food into cellular energy, transporting energy within cells, repairing damaged DNA, etc. In short, it is the mission critical coenzyme in cellular metabolism.There is plenty of research available on-line with respect to the critical role that NAD+ plays in cellular health, but one of the best (maybe not the most accessible if you need a biology refresher) is from Science Magazine here.2) Cellular NAD+ concentrations change during aging and the decline in NAD+ levels leads to aging-related diseases and maladies. There is a substantial amount of research ongoing currently about the role that NAD+ depletion plays in age-related obesity, diabetes, heart disease, certain cancers, neurodegenerative diseases (Parkinson's, Alzheimer’s etc.), and autoimmune diseases.3) The ability to supplement the bodies declining stores of NAD+ as it ages should produce longer and healthier lifespans by forestalling (and perhaps eliminating) many of the diseases, maladies, and characteristics that are currently assumed to be byproducts of aging.4) Nicotinamide riboside (which is found in trace amounts in milk) is a Vitamin B3 metabolite that has shown to substantially raise NAD+ levels in humans. Niacin is also a Vitamin B3 metabolite but it has far less bioavailability than NR and produces an unpleasant flushing side effect if taken in recommended doses. All the available research has shown that NR is the best Vitamin B3 metabolite precursor to NAD+.5) In late-2015 Chromadex received New Dietary Ingredient status for Niagen from the FDA and in August-2016 the FDA issued Chromadex a GRAS No Objection letter deeming the product safe.6) As can be seen in the company's presentation there is a slew of research underway now to study what role declining NAD+ plays in a whole host of conditions and diseases. As the single source patented supplier of NR in the US the company has a very large addressable market for Niagen.

★★★★★ This is a refill so see my prior review for details. The science is promising (but not enough yet to make it a sure thing) but the price is reasonable and their customer service is great if you need to call them. I'm willing to pay a dollar a day and hope for results to help me age gracefully. In addition, to my first review I should also mention this didn't make a difference in my ongoing gym performance. I stick to standard gym equipment (5 days a week 30 minutes to 2 hours) though and I can't speak to the results for extreme athletics.

★★★★★ Let me start by saying that I do not write reviews that often, but I felt compelled after using this product for more than 4 weeks. A little bit about my demographic. I am almost 30 years old, I did six years active duty in the marines and also competed in mixed martial arts, as well as competed in cross country at the college level. To put it simply, at nearly 30 years old, my body was feeling a little worn out, and at times I felt my short term memory and overall energy groggy at best. I was a staunch coffee/caffeine drinker to boot. Now that I have explained my reasoning and why this product seemed to be a good fit for someone like myself, I will say that this product works tremendously. I will also add that it took roughly 4 weeks to see a noticeable worthwhile change. Around 2 weeks or so into taking the product, my memory felt sharper and my overall energy began to rise. At the approximate 4 week mark, I felt healthier, sharper, and had lasting energy that went into the evening hours. To add, now that I am at the 6 week mark, I know I will continue to use this product going forward. This product is as advertised as long as you give it the time to work. I really hope this product represents the start of a new turn in the health industry that helps people of all ages live a better, happier, and healthier lifestyle. One side note to mention: I had vivid dreams for the first 2-3 weeks of taking this product. My dreams have seemed to normalize now, to a degree, but there was a huge noticeable difference in my sleeping patterns after the first few days. I would say that I felt more rested when I woke up the next morning for sure, but my deams in the REM state were extremely vivid.